Human influenza

Tracking the emergence of antigenic variants in influenza A virus epidemics in Brazil

Pillai TK, Johnson KE, Song T, Gregianini TS, Tatiana G B, Wang G, Medina RA, Van Bakel H, García-Sastre A, Nelson MI, Ghedin E, Veiga ABG

Virus Evol · 2023 · 9(1):vead027

Birth cohort relative to an influenza A virus's antigenic cluster introduction drives patterns of children's antibody titers

Brouwer AF, Balmaseda A, Gresh L, Patel M, Ojeda S, Schiller AJ, Lopez R, Webby RJ, Nelson MI, Kuan G, Gordon A

PLoS Pathog · 2022 · 18(2):e1010317

Homotypic protection against influenza in a pediatric cohort in Managua, Nicaragua

Wraith S, Balmaseda A, Carrillo FAB, Kuan G, Huddleston J, Kubale J, Lopez R, Ojeda S, Schiller A, Lopez B, Sanchez N, Webby R, Nelson MI, Harris E, Gordon A

Nat Commun · 2022 · 13(1):1190

Beyond clinical trials: Evolutionary and epidemiological considerations for development of a universal influenza vaccine

Viboud C, Gostic K, Nelson MI, Price GE, Perofsky A, Sun K, Sequeira Trovão N, Cowling BJ, Epstein SL, Spiro DJ

PLoS Pathog · 2020 · 16(9):e1008583

Review

Human Influenza A Virus Hemagglutinin Glycan Evolution Follows a Temporal Pattern to a Glycan Limit

Altman MO, Angel M, Košík I, Trovão NS, Zost SJ, Gibbs JS, Casalino L, Amaro RE, Hensley SE, Nelson MI, Yewdell JW

mBio · 2019 · 10(2)

Origins of the 1918 Pandemic: Revisiting the Swine "Mixing Vessel" Hypothesis

Nelson MI, Worobey M

Am J Epidemiol · 2018 · 187(12):2498-2502

Review

Phylogeography of Influenza A(H3N2) Virus in Peru, 2010-2012

Pollett S, Nelson MI, Kasper M, Tinoco Y, Simons M, Romero C, Silva M, Lin X, Halpin RA, Fedorova N, Stockwell TB, Wentworth D, Holmes EC, Bausch DG

Emerg Infect Dis · 2015 · 21(8):1330-8

Molecular epidemiology of influenza A/H3N2 viruses circulating in Mexico from 2003 to 2012

Escalera-Zamudio M, Nelson MI, Cobián Güemes AG, López-Martínez I, Cruz-Ortiz N, Iguala-Vidales M, García ER, Barrera-Badillo G, Díaz-Quiñonez JA, López S, Arias CF, Isa P, Members of Colegio de Pediatría del Estado de Veracruz

PLoS One · 2014 · 9(7):e102453

★ Featured publication

Multiyear persistence of 2 pandemic A/H1N1 influenza virus lineages in West Africa

Nelson MI, Njouom R, Viboud C, Niang MN, Kadjo H, Ampofo W, Adebayo A, Tarnagda Z, Miller MA, Holmes EC, Diop OM

J Infect Dis · 2014 · 210(1):121-5

The evolutionary dynamics of influenza A and B viruses in the tropical city of Managua, Nicaragua

Nelson MI, Balmaseda A, Kuan G, Saborio S, Lin X, Halpin RA, Stockwell TB, Wentworth DE, Harris E, Gordon A

Virology · 2014 · 462-463:81-90

Contrasting the epidemiological and evolutionary dynamics of influenza spatial transmission

Viboud C, Nelson MI, Tan Y, Holmes EC

Philos Trans R Soc Lond B Biol Sci · 2013 · 368(1614):20120199

Review

Epidemiological dynamics and phylogeography of influenza virus in southern China

Cheng X, Tan Y, He M, Lam TT, Lu X, Viboud C, He J, Zhang S, Lu J, Wu C, Fang S, Wang X, Xie X, Ma H, Nelson MI, Kung HF, Holmes EC, Cheng J

J Infect Dis · 2013 · 207(1):106-14

Global influenza seasonality: reconciling patterns across temperate and tropical regions

Tamerius J, Nelson MI, Zhou SZ, Viboud C, Miller MA, Alonso WJ

Environ Health Perspect · 2011 · 119(4):439-45

Review

Phylogeography of the spring and fall waves of the H1N1/09 pandemic influenza virus in the United States

Nelson MI, Tan Y, Ghedin E, Wentworth DE, St George K, Edelman L, Beck ET, Fan J, Lam TT, Kumar S, Spiro DJ, Simonsen L, Viboud C, Holmes EC, Henrickson KJ, Musser JM

J Virol · 2011 · 85(2):828-34

Temporally structured metapopulation dynamics and persistence of influenza A H3N2 virus in humans

Bahl J, Nelson MI, Chan KH, Chen R, Vijaykrishna D, Halpin RA, Stockwell TB, Lin X, Wentworth DE, Ghedin E, Guan Y, Peiris JS, Riley S, Rambaut A, Holmes EC, Smith GJ

Proc Natl Acad Sci U S A · 2011 · 108(48):19359-64

The early diversification of influenza A/H1N1pdm

Nelson M, Spiro D, Wentworth D, Beck E, Fan J, Ghedin E, Halpin R, Bera J, Hine E, Proudfoot K, Stockwell T, Lin X, Griesemer S, Kumar S, Bose M, Viboud C, Holmes E, Henrickson K

PLoS Curr · 2009 · 1:RRN1126

The origin and global emergence of adamantane resistant A/H3N2 influenza viruses

Nelson MI, Simonsen L, Viboud C, Miller MA, Holmes EC

Virology · 2009 · 388(2):270-8

Molecular epidemiology of A/H3N2 and A/H1N1 influenza virus during a single epidemic season in the United States

Nelson MI, Edelman L, Spiro DJ, Boyne AR, Bera J, Halpin R, Sengamalay N, Ghedin E, Miller MA, Simonsen L, Viboud C, Holmes EC

PLoS Pathog · 2008 · 4(8):e1000133

★ Featured publication

Multiple reassortment events in the evolutionary history of H1N1 influenza A virus since 1918

Nelson MI, Viboud C, Simonsen L, Bennett RT, Griesemer SB, St George K, Taylor J, Spiro DJ, Sengamalay NA, Ghedin E, Taubenberger JK, Holmes EC

PLoS Pathog · 2008 · 4(2):e1000012

The genomic and epidemiological dynamics of human influenza A virus

Rambaut A, Pybus OG, Nelson MI, Viboud C, Taubenberger JK, Holmes EC

Nature · 2008 · 453(7195):615-9

Phylogenetic analysis reveals the global migration of seasonal influenza A viruses

Nelson MI, Simonsen L, Viboud C, Miller MA, Holmes EC

PLoS Pathog · 2007 · 3(9):1220-8

★ Featured publication

The evolution of epidemic influenza

Nelson MI, Holmes EC

Nat Rev Genet · 2007 · 8(3):196-205

Review

Stochastic processes are key determinants of short-term evolution in influenza a virus

Nelson MI, Simonsen L, Viboud C, Miller MA, Taylor J, George KS, Griesemer SB, Ghedin E, Sengamalay NA, Spiro DJ, Volkov I, Grenfell BT, Lipman DJ, Taubenberger JK, Holmes EC

PLoS Pathog · 2006 · 2(12):e125