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Multiyear persistence of 2 pandemic A/H1N1 influenza virus lineages in West Africa (opens in a new tab)

Nelson MI, Njouom R, Viboud C, Niang MN, Kadjo H, Ampofo W, Adebayo A, Tarnagda Z, Miller MA, Holmes EC, Diop OM

J Infect Dis 2014 210(1):121-5

Human influenza MISMS

DOI 10.1093/infdis/jiu047 (opens in a new tab) PubMed ID 24446525 (opens in a new tab) PubMed Central PMC4162001 (opens in a new tab) Download PDF (opens in a new tab)

Abstract

Our understanding of the global ecology of influenza viruses is impeded by historically low levels of viral surveillance in Africa. Increased genetic sequencing of African A/H1N1 pandemic influenza viruses during 2009-2013 revealed multiyear persistence of 2 viral lineages within West Africa, raising questions about the roles of reduced air traffic and the asynchrony of seasonal influenza epidemics among West African countries in the evolution of independent lineages. The potential for novel influenza virus lineages to evolve within Africa warrants intensified influenza surveillance in Africa and other understudied areas.

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